An AIE Metal Iridium Complex: Photophysical Properties and Singlet Oxygen Generation Capacity

An AIE Metal Iridium Complex: Photophysical Properties and Singlet Oxygen Generation Capacity

Blog Article

Photodynamic therapy (PDT) has garnered significant attention in the fields of cancer treatment and drug-resistant bacteria eradication due to its non-invasive nature and spatiotemporal controllability.Iridium complexes have captivated researchers owing to their tunable structure, exceptional optical properties, and substantial Stokes displacement.However, most of these complexes suffer from aggregation-induced quenching, leading to diminished luminous efficiency.In Bracket contrast to conventional photosensitizers, photosensitizers exhibiting aggregation-induced luminescence (AIE) properties retain the ability to generate a large number of reactive oxygen species when aggregated.To overcome these limitations, we designed and synthesized a novel iridium complex named Ir-TPA in this study.

It incorporates quinoline triphenylamine cyclomethylated ligands that confer AIE characteristics for Ir-TPA.We systematically investigated the photophysical properties, AIE behavior, Dab Inserts spectral features, and reactive oxygen generation capacity of Ir-TPA.The results demonstrate that Ir-TPA exhibits excellent optical properties with pronounced AIE phenomenon and robust capability for producing singlet oxygen species.This work not only introduces a new class of metal iridium complex photosensitizer with AIE attributes but also holds promise for achieving remarkable photodynamic therapeutic effects in future cellular experiments and biological studies.